
The engine adapts to the fuel that is in the tank, from petrol to E85 and any blend in between. This is not a fixed E85 calibration. 42 engines.
| Engine | Generation | Fuel | Stock | ECU | Read tools |
|---|---|---|---|---|---|
| S450 | W223 2021 | Petrol | 367 hp | Bosch MG1CP002 | Autotuner, FLEX |
| S500 | W223 2021 | Petrol | 450 hp | Bosch MG1CP002, Bosch MG1CS046 | Autotuner, FLEX |
| 580 (4.0T) | W223 2021 | Petrol | 503 hp | Bosch MG1CP004 | |
| 580e | W223 2021 | Petrol hybrid | 510 hp | Bosch MG1CP004 | FLEX |
| 580 MHEV | W223 2021 | Petrol | 537 hp | Bosch MG1CP003 | Autotuner |
| 580e PHEV | W223 2021 | Petrol plug-in hybrid | 585 hp | Bosch MG1CS046 | Autotuner |
| S450 | W222 2017 - 2021 | Petrol | 367 hp | Bosch MED17.7.3.1, Bosch MG1CP002 | Autotuner, FLEX |
| 450 EQ Boost | W222 2017 - 2021 | Petrol (mild hybrid) | 389 hp | Bosch MG1CP002 | FLEX |
| S560 | W222 2017 - 2021 | Petrol | 469 hp | Bosch MED17.7.5 | FLEX |
| 560 E | W222 2017 - 2021 | Petrol hybrid | 489 hp | ||
| 63 AMG S - 4.0 V8 BiTurbo | W222 2017 - 2021 | Petrol | 612 hp | Bosch MED17.7.5 | FLEX |
| S 65 AMG | W222 2017 - 2021 | Petrol | 630 hp | Bosch ME17.7.8 | FLEX |
| S 300 CDI Hybrid | W217/222 2014 - 2017 | Petrol hybrid | 231 hp | Delphi CRD3 | FLEX |
| 400 Hybrid (3.5i) | W217/222 2014 - 2017 | Petrol plug-in hybrid | 306 hp | Bosch MED17.7.1, Bosch MED17.7.3 | Autotuner |
| S 400 | W217/222 2014 - 2017 | Petrol | 333 hp | Bosch MED17.7.3.1, Bosch MG1CP002 | Autotuner |
| S 400 Hybrid | W217/222 2014 - 2017 | Petrol | 333 hp | Bosch MED17.7.3.1, Bosch MG1CP002 | Autotuner |
| S 400 | W217/222 2014 - 2017 | Petrol | 367 hp | Bosch MED17.7.3.1 | Autotuner |
| 550 EU6 (4.7T) | W217/222 2014 - 2017 | Petrol | 408 hp | Bosch MED17.7.1, Bosch MED17.7.3 | Autotuner |
| 500 | W217/222 2014 - 2017 | Petrol | 422 hp | Autotuner | |
| S 500 | W217/222 2014 - 2017 | Petrol | 455 hp | Bosch MED17.7.1, Bosch MED17.7.3 | Autotuner, FLEX |
| 560 EU6 (4.0T) | W217/222 2014 - 2017 | Petrol | 463 hp | Bosch MED17.7.5 | Autotuner |
| S 600 | W217/222 2014 - 2017 | Petrol | 530 hp | Bosch MED17.7.8 | Autotuner |
| S 63 AMG | W217/222 2014 - 2017 | Petrol | 585 hp | Bosch MED17.7.1, Bosch MED17.7.3 | Autotuner |
| S 63 AMG S - 4.0 Bi Turbo | W217/222 2014 - 2017 | Petrol | 612 hp | Bosch MED17.7.5 | Autotuner |
| S 65 AMG | W217/222 2014 - 2017 | Petrol | 630 hp | Bosch ME17.7.8 | Autotuner, FLEX |
| 350 (3.5i) | W221 2006 - 2013 | Petrol | 272 hp | Bosch ME17.7, Bosch ME9.7, Bosch MED17.7.1 | Autotuner, FLEX |
| 400 Hybrid (3.5) | W221 2006 - 2013 | Petrol plug-in hybrid | 279 hp | Bosch ME9.7 | Autotuner |
| S 400 Hybrid | W221 2006 - 2013 | Petrol hybrid | 299 hp | Bosch ME17.7, Bosch ME9.7 | FLEX |
| 450 (4.7i) | W221 2006 - 2013 | Petrol | 340 hp | Bosch ME9.7, Bosch MED17.7.3 | Autotuner, FLEX |
| S 500 | W221 2006 - 2013 | Petrol | 388 hp | Bosch ME9.7 | Autotuner, FLEX |
| S 550 | W221 2006 - 2013 | Petrol | 435 hp | Bosch MED17.7.1, Bosch MED17.7.3 | Autotuner |
| S 500 | W221 2006 - 2013 | Petrol | 435 hp | Bosch MED17.7.1 | |
| S 600 | W221 2006 - 2013 | Petrol | 517 hp | Bosch ME2.7.2 | |
| S 63 AMG | W221 2006 - 2013 | Petrol | 525 hp | Bosch ME9.7 | Autotuner |
| S 63 AMG | W221 2006 - 2013 | Petrol | 544 hp | Bosch MED17.7.1, Bosch MED17.7.3 | Autotuner |
| 63 AMG Perf. (5.5T) | W221 2006 - 2013 | Petrol | 571 hp | Bosch MED17.7.1, Bosch MED17.7.3 | Autotuner |
| S 65 AMG | W221 2006 - 2013 | Petrol | 612 hp | ||
| 350 (3.7i) | W220 2002 - 2005 | Petrol | 245 hp | Bosch ME2.8 | Autotuner |
| 430 4Matic | W220 2002 - 2005 | Petrol | 279 hp | Bosch ME2.0, Bosch ME2.8 | |
| 500 (5.0i) | W220 2002 - 2005 | Petrol | 306 hp | Bosch ME2.8 | Autotuner |
| 55 AMG | W220 2002 - 2005 | Petrol | 360 hp | Bosch ME2.8 | Autotuner |
| S 55 AMG | W220 2002 - 2005 | Petrol | 500 hp | Bosch ME2.8.1 | Autotuner |
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